GUILDERLAND – There she goes again.

Serial entrepreneur, Lisa Fasulo, has opened her next venture in the Capital Region: Michelangelo’s Paint Place.

Enterprise readers will know Fasulo from her former business, a tattoo shop and school, which she sold, and her current business, Websites While U Wait, which she still runs.

Her latest business, as she describes it, is a happy place borne of tragedy.

It is named after Michael Fasulo – Lisa’s ex-husband, with whom she remained close, and the father of her daughters, Alexandra and Allegra – who died tragically last year.

Hard work is one way that she and her daughters coped, Faulo said.

“We were devastated,” Fasulo said. “I just felt a call to do something that is more fun. We needed some happiness and we wanted to be around friends.”

Fasulo was inspired to get back to her artistic roots, she said, and make something happy. “At my core, I am an artist,” she said. “I didn't have to reinvent the wheel.”

Michelangelo’s Paint Place is not a memorial to Michael, she said. Rather, he inspired it; Michael was also an artist. Alexandra and Allegra are artists in their own right, their mother added. He was the son of the late Marijo Dougherty, an artist and curator.

Allegra Fasulo is starting her own line of athleisure wear in the next few weeks, and, Alexandra has been so successful on Fiverr, an online marketplace for freelance services, that CNBC has reached out to do a story on all that she’s accomplished, her mother said.

Located at 2568 Western Ave. in Guilderland in the Carpenter Plaza, Michelangelo’s is not a “paint and sip” shop; no alcohol is served. It offers painting parties, T-shirt-painting parties, kids’ parties, and open paint hours to kids of every age and background as well as one-on-one lessons.

“I just love teaching art … it helps people relax. It’s a chance for them to put their phone down,” Fasulo said. “It is a nice time to just chat and relax. I think people are looking for that.”

An enterprising ethos is a family trait that has been passed down from generation to generation in the Fasulo family.

Fasulo’s grandfather, on her mother’s side, owned an an electrical supply company that he kept afloat during the Great Depression, which was a success after the Depression ended. Her father then took over the business and brought it to greater heights, Fasulo said.

She still has her grandfather’s old bookkeeping ledgers, where profits were written in black ink and losses in red. “I really treasure them because I like to show the kids that Pop survived through the hard times; here is the proof,” Fasulo said.

Fasulo attributes her success to a “lack of fear.”

“We don’t fear failure because we know, if you put in the hard work, you are not going to fail. You just need to keep solving problems,” she said.